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2. Vaso-occlusive crisis - Wikipedia

   en.wikipedia.org/wiki/Vaso-occlusive_crisis

   A vaso-occlusive crisis is a common painful complication of sickle cell anemia in adolescents and adults. It is a form of sickle cell crisis. Sickle cell anemia – most common in those of African, Hispanic, and Mediterranean origin – leads to sickle cell crisis when the circulation of blood vessels is obstructed by sickled red blood cells, causing ischemic injuries. The most common ...

3. Exagamglogene autotemcel - Wikipedia

   en.wikipedia.org/wiki/Exagamglogene_autotemcel

   DrugBank. DB15572. UNII. S53L777GM8. KEGG. D12749. Exagamglogene autotemcel, sold under the brand name Casgevy, is a gene therapy used for the treatment of sickle cell disease [1] [3] and transfusion-dependent beta thalassemia. [1] It was developed by Vertex Pharmaceuticals and CRISPR Therapeutics.

4. Crizanlizumab - Wikipedia

   en.wikipedia.org/wiki/Crizanlizumab

   Molar mass. 146 232.04 g·mol −1. Crizanlizumab, sold under the brand name Adakveo among others, is a monoclonal antibody medication that binds to P-selectin. [3] It is a medication used to reduce the frequency of vaso-occlusive crisis in people aged 16 years and older who have sickle cell anemia. [3] [4] [6] It is given by injection into a vein.

5. FDA approves cure for sickle cell disease, the first ... - AOL

   www.aol.com/news/fda-approves-cure-sickle-cell...

   December 8, 2023 at 10:19 AM. The Food and Drug Administration on Friday approved a powerful treatment for sickle cell disease, a devastating illness that affects more than 100,000 Americans, the ...

6. FDA considers first CRISPR gene editing treatment that may ...

   www.aol.com/fda-considers-first-crispr-gene...

   In company studies, the treatment was considered safe, and it had a “highly positive benefit-risk for patients with severe sickle cell disease,” Dr. Stephanie Krogmeier, vice president for ...

7. New sickle cell treatment sparks feelings of hope and some ...

   www.aol.com/news/sickle-cell-treatment-sparks...

   While sickle cell disease is most known for causing severe pain, patients can experience stroke, heart disease, organ damage and a dangerous condition called acute chest syndrome caused by ...