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  2. Heterozygote advantage - Wikipedia

    en.wikipedia.org/wiki/Heterozygote_advantage

    A heterozygote advantage describes the case in which the heterozygous genotype has a higher relative fitness than either the homozygous dominant or homozygous recessive genotype. Loci exhibiting heterozygote advantage are a small minority of loci. [1] The specific case of heterozygote advantage due to a single locus is known as overdominance.

  3. Normal distribution - Wikipedia

    en.wikipedia.org/wiki/Normal_distribution

    Probability theory. In probability theory and statistics, a normal distribution or Gaussian distribution is a type of continuous probability distribution for a real-valued random variable. The general form of its probability density function is. The parameter is the mean or expectation of the distribution (and also its median and mode ), while ...

  4. Genetic history of Africa - Wikipedia

    en.wikipedia.org/wiki/Genetic_history_of_Africa

    Some may have migrated into and introduced the Senegal and Benin sickle cell haplotypes into Basra, Iraq, where both occur equally. West Africans, bearing the Benin sickle cell haplotype, may have migrated into the northern region of Iraq (69.5%), Jordan (80%), Lebanon (73%), Oman (52.1%), and Egypt (80.8%). Schistosomes

  5. Hemoglobin electrophoresis - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_electrophoresis

    Hemoglobin electrophoresis is a blood test that can detect different types of hemoglobin. The test can detect hemoglobin S, the form associated with sickle cell disease, as well as other abnormal types of hemoglobin, such as hemoglobin C. It can also be used to investigate thalassemias, which are disorders caused by defective hemoglobin production.

  6. Mean corpuscular hemoglobin concentration - Wikipedia

    en.wikipedia.org/wiki/Mean_corpuscular...

    The mean corpuscular hemoglobin concentration (MCHC) is a measure of the concentration of hemoglobin in a given volume of packed red blood cell. It is calculated by dividing the hemoglobin by the hematocrit. Reference ranges for blood tests are 32 to 36 g/dL (320 to 360g/L), or between 4.81 and 5.58 mmol/L. It is thus a mass or molar concentration.

  7. Sickle Cell Anemia, a Molecular Disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_Cell_Anemia,_a...

    The molecular disease concept put forward in the 1949 paper also became the basis for Linus Pauling's view of evolution. In the 1960s, by which time it had been shown that sickle cell trait confers resistance to malaria and so the gene had both positive and negative effects and demonstrated heterozygote advantage, Pauling suggested that ...

  8. Race and health - Wikipedia

    en.wikipedia.org/wiki/Race_and_health

    t. e. Race and health refers to how being identified with a specific race influences health. Race is a complex concept that has changed across chronological eras and depends on both self-identification and social recognition. [1] In the study of race and health, scientists organize people in racial categories depending on different factors such ...

  9. Plasmodium falciparum - Wikipedia

    en.wikipedia.org/wiki/Plasmodium_falciparum

    Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans. [2] The parasite is transmitted through the bite of a female Anopheles mosquito and causes the disease's most dangerous form, falciparum malaria. It is responsible for around 50% of all malaria cases.

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