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The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]
Raycom acquired the assets of live and studio sports programming production company Tupelo-Honey Productions in January 2012. Tupelo Honey assets included a 50% share of MY Tupelo Entertainment, a joint venture form in 2009 as partnership between Cary Glotzer's Tupelo-Honey and Michael Yudin's MY-Entertainment Company.
Ronald Wilson Reagan [a] (February 6, 1911–June 5, 2004) was an American politician and actor who served as the 40th president of the United States from 1981 to 1989. A member of the Republican Party, his presidency constituted the Reagan era, and he is considered one of the most prominent American conservative figures.
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About 50% of people who die of suicide have a mood disorder such as major depression. [ 175 ] [ 176 ] Sleep and diet may play a role in depression ( major depressive disorder ), and interventions in these areas may be an effective add-on to conventional methods. [ 177 ]
Shell plc is a British multinational oil and gas company headquartered in London, England. [5] Shell is a public limited company with a primary listing on the London Stock Exchange (LSE) and secondary listings on Euronext Amsterdam and the New York Stock Exchange.