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  2. Huntington's disease - Wikipedia

    en.wikipedia.org/wiki/Huntington's_disease

    Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease [7] that is mostly inherited. [8] The earliest symptoms are often subtle problems with mood or mental/psychiatric abilities. [9][1] A general lack of coordination and an unsteady gait often follow. [2] It is also a basal ganglia disease ...

  3. Trinucleotide repeat disorder - Wikipedia

    en.wikipedia.org/wiki/Trinucleotide_repeat_disorder

    These often are translated into polyglutamine-containing proteins that form inclusions and are toxic to neuronal cells. Examples of the disorders caused by this mechanism include Huntington's disease and Huntington disease-like 2, spinal-bulbar muscular atrophy, dentatorubral-pallidoluysian atrophy, and spinocerebellar ataxia 1–3, 6–8, and 17.

  4. Hyperkinesia - Wikipedia

    en.wikipedia.org/wiki/Hyperkinesia

    Hyperkinesia refers to an increase in muscular activity that can result in excessive abnormal movements, excessive normal movements, or a combination of both. [1] Hyperkinesia is a state of excessive restlessness which is featured in a large variety of disorders that affect the ability to control motor movement, such as Huntington's disease.

  5. Tetrabenazine - Wikipedia

    en.wikipedia.org/wiki/Tetrabenazine

    Tetrabenazine is a drug for the symptomatic treatment of hyperkinetic movement disorders. It is sold under the brand names Nitoman and Xenazine among others. On August 15, 2008, the U.S. Food and Drug Administration approved the use of tetrabenazine to treat chorea associated with Huntington's disease. Although other drugs had been used " off ...

  6. Huntington's Disease Association - Wikipedia

    en.wikipedia.org/wiki/Huntington's_Disease...

    George Rainsford (patron) Website. www .hda .org .uk. The Huntington's Disease Association ( HDA) is a charity that supports people in England and Wales affected by the genetic neurodegenerative brain condition Huntington's disease (HD). The HDA was founded in 1986 and is based in Liverpool. [1] It supports a network of regional care advisors ...

  7. Huntington's Disease Society of America - Wikipedia

    en.wikipedia.org/wiki/Huntington's_Disease...

    The Society comprises 50+ volunteer-led local chapters and affiliates across the country with its headquarters in New York City. Additionally, HDSA hosts more than 200 support groups for people with HD, their families, caregivers and people at-risk, and is a resource on Huntington's Disease for medical professionals and the general public. [1]

  8. Basal ganglia disease - Wikipedia

    en.wikipedia.org/wiki/Basal_ganglia_disease

    Basal ganglia disease. Basal ganglia disease is a group of physical problems that occur when the group of nuclei in the brain known as the basal ganglia fail to properly suppress unwanted movements or to properly prime upper motor neuron circuits to initiate motor function. [1] Research indicates that increased output of the basal ganglia ...

  9. Journal of Huntington's Disease - Wikipedia

    en.wikipedia.org/wiki/Journal_of_Huntington's...

    The Journal of Huntington 's Disease is a quarterly peer-reviewed scientific journal in neuroscience that covers all aspects of Huntington's disease and related disorders. It was established in 2012 and is published by IOS Press. The editors-in-chief are Blair Leavitt ( University of British Columbia) and Leslie Thompson ( UC Irvine ).