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Sickle cell disease ( SCD ), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. [2] The most common type is known as sickle cell anemia. [2] It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2] This leads to a rigid, sickle -like shape under ...
Hematology. Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous ), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous ). Those who are heterozygous for the sickle cell allele produce ...
The Manstein Plan or Case Yellow ( German: Fall Gelb; also known after the war as Unternehmen Sichelschnitt a transliteration of the English Operation Sickle cut ), was the war plan of the German armed forces ( Wehrmacht) for the Battle of France in 1940. The original invasion plan was an awkward compromise devised by General Franz Halder, the ...
Genetic history of Europe. The European genetic structure today (based on 273,464 SNPs). Three levels of structure as revealed by PC analysis are shown: A) inter-continental; B) intra-continental; and C) inside a single country (Estonia), where median values of the PC1&2 are shown. D) European map illustrating the origin of sample and ...
Sickle cell-beta thalassemia is caused by inheritance of a sickle cell allele from one parent and a beta thalassemia allele from the other. Mutations. A sickle allele is always the same mutation of the beta-globin gene (glutamic acid to valine at amino acid six). In contrast, beta-thalassemia alleles can be created by many different mutations ...
Haplogroup E-M2, also known as E1b1a1-M2, is a human Y-chromosome DNA haplogroup.E-M2 is primarily distributed within Africa followed by West Asia. More specifically, E-M2 is the predominant subclade in West Africa, Central Africa, Southern Africa, and the region of the African Great Lakes; it also occurs at moderate frequencies in North Africa, and the Middle East.
In March 2017, the population of France officially reached the 67,000,000 mark. It had reached 66,000,000 in early 2014. [6] Between the years 2010–17, the population of France grew from 64,613,000 to 66,991,000 (i.e. about 2.4 million people in a span of 7 years), making France one of the fastest-growing countries in Europe.
Stripes of red and white have been a collective emblem of Austria for over 800 years, and they were first used on the flag in 1191. According to long-established legend, the red and white flag was designed to resemble the bloodstained white coat worn by the Duke of Austria during a fierce battle. 1918–1920. 1991–.