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Oneworld (stylised as oneworld; CRS: *O) is a global airline alliance consisting of 15 member airlines. It was founded on 1 February 1999. The alliance's stated objective is to be the first choice airline alliance for the world's frequent international travellers.
However, due to first-pass metabolism in the liver and the high lipid solubility of THC, only about 5 to 20% reaches circulation. [ 3 ] [ 21 ] Following oral administration, concentrations of THC and its major active metabolite 11-hydroxy-THC (11-OH-THC) peak after 0.5 to 4 hours, with median time to peak of 1.0 to 2.5 hours at different doses.