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Sickle cell test. A urologist might request this test for men with a higher risk of sickle cell disease. Duplex ultrasound. Sometimes called ultrasonography, this can measure blood flow in your ...
By way of analogy, the allele (a particular version of a gene) which causes sickle cell disease when two copies are present, also confers an adaptive advantage when one copy is present by providing resistance to malaria with non-symptomatic sickle cell trait—which is known as "heterozygote advantage". [96]
Sickle-cell anemia, which can cause blood cells to clump up and block blood vessels, can also lead to stroke. Stroke is the second leading cause of death in people under 20 with sickle-cell anemia. [52] Air pollution may also increase stroke risk. [53]
For example, sickle-cell anemia is a human genetic disease that results from a single base difference within the coding region for the β-globin section of hemoglobin, causing a single amino acid change that changes hemoglobin's physical properties. [78]
The classic symptoms of untreated coeliac disease include diarrhea, steatorrhoea, iron-deficiency anemia, and weight loss or failure to gain weight. Other common symptoms may be subtle or primarily occur in organs other than the bowel itself. [33] It is also possible to have coeliac disease without any of the classic symptoms at all. [18]
Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. [ 4 ][ 5 ] These areas are red, pink, or purple, dry, itchy, and scaly. [ 8 ][ 3 ] Psoriasis varies in severity from small localized patches to complete body coverage. [ 3 ] Injury to the skin can trigger psoriatic skin changes at that spot ...
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling chronic illness. People with ME/CFS experience profound fatigue that does not go away with rest, sleep issues, and problems with memory or concentration. Further common symptoms include dizziness, nausea and pain. [3] The hallmark symptom is a worsening of the illness ...
Symptoms: Chest pain, fatigue [2] Usual onset: 20 to 60 years old [3] Duration: Long term [4] Causes: Unknown [4] Risk factors: Family history, pulmonary embolism, HIV/AIDS, sickle cell disease, cocaine use, COPD, sleep apnea, living at high altitudes [5] [3] Diagnostic method: Following ruling out other potential causes [4] Treatment