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  2. Vaso-occlusive crisis - Wikipedia

    en.wikipedia.org/wiki/Vaso-occlusive_crisis

    A vaso-occlusive crisis is a common painful complication of sickle cell anemia in adolescents and adults. [1] [2] It is a form of sickle cell crisis.Sickle cell anemia – most common in those of African, Hispanic, and Mediterranean origin – leads to sickle cell crisis when the circulation of blood vessels is obstructed by sickled red blood cells, causing ischemic injuries.

  3. Pfizer withdraws sickle cell disease treatment on risk of ...

    www.aol.com/news/pfizer-withdraws-sickle-cell...

    The company added that the data shows an imbalance in vaso-occlusive crises, a complication of the disease and "fatal events" that requires further assessment. Vaso-occlusive crisis in patients ...

  4. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    It is the second-most common complication and it accounts for about 25% of deaths in patients with SCD. Most cases present with vaso-occlusive crises, and then develop acute chest syndrome. [33] [34] Nevertheless, about 80% of people have vaso-occlusive crises during acute chest syndrome. [35]

  5. Acute chest syndrome - Wikipedia

    en.wikipedia.org/wiki/Acute_chest_syndrome

    Acute chest syndrome. The acute chest syndrome is a vaso-occlusive crisis of the pulmonary vasculature commonly seen in people with sickle cell anemia. This condition commonly manifests with a new opacification of the lung (s) on a chest x-ray. [1]

  6. Crizanlizumab - Wikipedia

    en.wikipedia.org/wiki/Crizanlizumab

    Vaso-occlusive crisis is a common and painful complication of sickle cell disease that occurs when blood circulation is obstructed by sickled red blood cells (red cells are usually round and flexible, but sometimes many red cells in a person with sickle cell anemia will become rigid and crescent-shaped due to polymerization of hemoglobin). [11]

  7. Hepatic veno-occlusive disease - Wikipedia

    en.wikipedia.org/wiki/Hepatic_veno-occlusive_disease

    10-20%. Hepatic veno-occlusive disease (VOD) or veno-occlusive disease with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant and/or excessive exposure to hepatotoxic pyrrolizidine alkaloids.

  8. These Are 4 of the Most Common Complications of ... - AOL

    www.aol.com/4-most-common-complications-hyper...

    Y ou could argue that the complications of a disease, rather than the disease itself, create most of the problems associated with that condition. Take hypertrophic cardiomyopathy, or HCM, a ...

  9. Sickle cell nephropathy - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_nephropathy

    Sickle cell disease. Sickle cell nephropathy is a type of kidney disease associated with sickle cell disease which causes kidney complications as a result of sickling of red blood cells in the small blood vessels. The hypertonic and relatively hypoxic environment of the renal medulla, coupled with the slow blood flow in the vasa recta, favors ...

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