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  2. Hemoglobin C - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_C

    Since HbC does not polymerize as readily as HbS, there is less sickling in most cases. There are fewer acute vaso-occlusive events and therefore in some cases fewer sickle cell crises. The peripheral smear demonstrates mostly target cells, occasional hemoglobin C crystals, and only a few sickle cells.

  3. Sickle cell nephropathy - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_nephropathy

    Sickle cell nephropathy is a type of kidney disease associated with sickle cell disease which causes kidney complications as a result of sickling of red blood cells in the small blood vessels. The hypertonic and relatively hypoxic environment of the renal medulla , coupled with the slow blood flow in the vasa recta , favors sickling of red ...

  4. Exagamglogene autotemcel - Wikipedia

    en.wikipedia.org/wiki/Exagamglogene_autotemcel

    In the US, exagamglogene autotemcel is indicated for the treatment of sickle cell disease in people aged 12 years and older with recurrent vaso-occlusive crises, [4] and for the treatment of people with transfusion-dependent beta-thalassemia. [4] [14]

  5. Lovotibeglogene autotemcel - Wikipedia

    en.wikipedia.org/wiki/Lovotibeglogene_autotemcel

    Lovotibeglogene autotemcel, sold under the brand name Lyfgenia, is a lentiviral gene therapy used for the treatment of sickle cell disease. [1] [3] [4] [5]The most common side effects include stomatitis (mouth sores of the lips, mouth, and throat), low levels of platelets, white blood cells, and red blood cells, and febrile neutropenia (fever and low white blood cell count), consistent with ...

  6. Sickle cell-beta thalassemia - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell-beta_thalassemia

    Treatment is the same as for patients with sickle cell disease. Patients may receive hydroxyurea to induce the protective effects of increased fetal hemoglobin production. . They may also benefit from blood transfusions especially during vaso-occlusive cris

  7. Thalassemia - Wikipedia

    en.wikipedia.org/wiki/Thalassemia

    Thalassemias are inherited blood disorders that result in abnormal hemoglobin. [7] Symptoms depend on the type of thalassemia and can vary from none to severe. [1] Often there is mild to severe anemia (low red blood cells or hemoglobin) as thalassemia can affect the production of red blood cells and also affect how long the red blood cells live. [1]