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A genetic basis for this disease was proposed in 1915 by Cook and Meyer. The disease was named sickle-cell anaemia in 1922 by Verne Mason after several additional cases were reported. All the known cases had been reported in blacks and he concluded that this disease was confined to those of black African descent.
The National Heart, Lung, and Blood Institute ( NHLBI) is the third largest Institute of the National Institutes of Health, located in Bethesda, Maryland, United States. It is tasked with allocating about $3.6 billion in FY 2020 [1] in tax revenue to advancing the understanding of the following issues: development and progression of disease ...
The ESR is decreased in polycythemia, hyperviscosity, sickle cell anemia, leukemia, chronic fatigue syndrome, low plasma protein (due to liver or kidney disease) and congestive heart failure. Although increases in immunoglobulins usually increase the ESR, very high levels can reduce it again due to hyperviscosity of the plasma.
The disease is considered one of the major types of anemia, especially in Western Sudan where the sickle cell gene is frequent Sickle cell disease is the major haemoglobinopathy seen in Khartoum, the capital of Sudan. This may be attributed to the migration of tribes from western Sudan as a result of drought and desertification in the 1970s and ...
Sickle-cell disease was the genetic disorder to be linked to a mutation of a specific protein. Pauling introduced his fundamentally important concept of sickle cell anemia as a genetically transmitted molecular disease. This vein (4) shows the interaction between the malaria sporozoites (6) with sickle cells (3) and regular cells (1).
Specialty. Nephrology. Sickle cell nephropathy is a type of nephropathy associated with sickle cell disease which causes kidney complications as a result of sickling of red blood cells in the small blood vessels. The hypertonic and relatively hypoxic environment of the renal medulla, coupled with the slow blood flow in the vasa recta, favors ...
Socioeconomic factors are the related cause, alongside it presenting barriers to treatment in the disease. Sickle cell disease is more susceptible to be found in those of descent from places such as those in the Mediterranean, Italy, Turkey, and Greece, as well as Africa and regions of South and Central America.
Bolaji Badejo (Listen ⓘ) (23 August 1953 – 22 December 1992) was a Nigerian visual artist and actor. He was known for playing the Alien in Ridley Scott's 1979 film Alien. He was 6 feet 10 inches (208 cm) tall, a height which convinced Scott to cast him in the role.
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