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  2. FDA approves cure for sickle cell disease, the first ... - AOL

    www.aol.com/news/fda-approves-cure-sickle-cell...

    Berkeley Lovelace Jr. and Marina Kopf. December 8, 2023 at 10:19 AM. The Food and Drug Administration on Friday approved a powerful treatment for sickle cell disease, a devastating illness...

  3. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    When treating avascular necrosis of the bone in people with sickle cell disease, the aim of treatment is to reduce or stop the pain and maintain joint mobility. Current treatment options include resting the joint, physical therapy, pain-relief medicine, joint-replacement surgery, or bone grafting.

  4. Hydroxycarbamide - Wikipedia

    en.wikipedia.org/wiki/Hydroxycarbamide

    Hydroxycarbamide, also known as hydroxyurea, is a medication used in sickle-cell disease, essential thrombocythemia, chronic myelogenous leukemia, polycythemia vera, and cervical cancer. In sickle-cell disease it increases fetal hemoglobin and decreases the number of attacks. It is taken by mouth.

  5. A new cure for sickle cell disease may be coming. FDA ... - AOL

    www.aol.com/cure-sickle-cell-disease-may...

    The only cure for painful sickle cell disease today is a bone marrow transplant. But soon there may be a new cure that attacks the disorder at its genetic source.

  6. New sickle cell treatment sparks feelings of hope and some ...

    www.aol.com/news/sickle-cell-treatment-sparks...

    The FDA is reviewing a new drug for sickle cell disease that uses CRISPR to edit DNA. Black patients with the disease are excited and hopeful about the treatment.

  7. Fetal hemoglobin - Wikipedia

    en.wikipedia.org/wiki/Fetal_hemoglobin

    Treatment of sickle-cell disease Increasing the body's production of fetal hemoglobin is used as a strategy to treat sickle-cell disease . Main article: Sickle-cell disease ยง Hydroxyurea

  8. FDA approves gene therapy for sickle cell disease: 'One ... - AOL

    www.aol.com/fda-approves-gene-therapy-sickle...

    Federal officials Friday approved two gene therapy treatments for sickle cell disease, welcome news for thousands with the inherited blood disorder that causes terrible pain crises and early death.

  9. Lovotibeglogene autotemcel - Wikipedia

    en.wikipedia.org/wiki/Lovotibeglogene_autotemcel

    D12765. Lovotibeglogene autotemcel, sold under the brand name Lyfgenia, is a lentiviral gene therapy used for the treatment of sickle cell disease. [1] [3] [4] [5] The most common side effects include stomatitis (mouth sores of the lips, mouth, and throat), low levels of platelets, white blood cells, and red blood cells, and febrile neutropenia ...

  10. Sickle cell nephropathy - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_nephropathy

    Treatment Lifestyle. Management of sickle nephropathy is not separate from that of overall patient management. Three-year graft and patient survival in kidney transplant recipients with sickle nephropathy is lower when compared to those with other causes of end-stage kidney disease.

  11. Voxelotor - Wikipedia

    en.wikipedia.org/wiki/Voxelotor

    Voxelotor, sold under the brand name Oxbryta, is a medication used for the treatment of sickle cell disease. Voxelotor is the first hemoglobin oxygen-affinity modulator. Voxelotor has been shown to have disease-modifying potential by increasing hemoglobin levels and decreasing hemolysis indicators in sickle cell patients.