Ads
related to: sickle cell disease epidemiology- Safety and Side Effects
Review the Important Safety
Information for this treatment.
- Treatment Journey Video
Understand the steps
and what they entail.
- Patient Resources
See the discussion guides, FAQs,
support groups and more.
- Sign Up
Sign up today to get connected
with a Patient Educator.
- About The Therapy
Learn how this therapy may help
treat the disease. Watch the video.
- Learn How It Works
Visit the official patient site to
learn how this treatment works.
- Safety and Side Effects
Search results
Results From The WOW.Com Content Network
Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders typically inherited. The most common type is known as sickle cell anemia. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells.
Sickle cell-Hb Lepore Boston syndrome is a type of sickle cell disease (HbS) that differs from homozygous sickle cell disease where both parents carry sickle hemoglobin. In this variant one parent has the sickle cell hemoglobin the second parent has Hb Lepore Boston, the only one of the three variants described in association with HbS.
Sickle cell disease. In persons with sickle cell disease, high levels of fetal hemoglobin as found in a newborn or as found abnormally in persons with hereditary persistence of fetal hemoglobin, the HbF causes the sickle cell disease to be less severe. In essence the HbF inhibits polymerization of HbS.
Epidemiology. Hemoglobin C is found most abundantly in areas of West Africa, such as Nigeria, where Yorubas live. Hemoglobin C gene is found in 2-3% of African-Americans while 8% of African-Americans have hemoglobin S (Sickle) gene. Thus Hemoglobin SC disease is significantly more common than Hemoglobin CC disease.
Sickle-cell disease and resistance to malaria. In 1949 Allison participated in a vocational Oxford University Expedition to Mount Kenya. He took up the task of collecting blood samples from Kenyans for analyses of blood groups and genetic markers such as for sickle-cell disease.
Appointed to the staff of the MRC Epidemiology Research Unit at UWI in November 1972, the ground work was laid for newborn screening of sickle cell disease made possible by the expertise of Beryl who adapted methods for the diagnosis of the disease on samples taken from the umbilical cord.
Ads
related to: sickle cell disease epidemiology