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  2. HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/HIV/AIDS

    HIV is now known to spread between CD4 + T cells by two parallel routes: cell-free spread and cell-to-cell spread, i.e. it employs hybrid spreading mechanisms. [96] In the cell-free spread, virus particles bud from an infected T cell, enter the blood/extracellular fluid and then infect another T cell following a chance encounter. [96]

  3. National Crisis Management Cell - Wikipedia

    en.wikipedia.org/.../National_Crisis_Management_Cell

    The National Crisis Management Cell was established in 2001 to tackle domestic and foreign terrorism, and to eliminate religious extremism in the country. [4] Its influence and role in the intelligence community included issuing warnings and formulating efforts against all kinds of threats posed to the state. [ 4 ]

  4. Sickle - Wikipedia

    en.wikipedia.org/wiki/Sickle

    A sickle, bagging hook, reaping-hook or grasshook is a single-handed agricultural tool designed with variously curved blades and typically used for harvesting or reaping grain crops, or cutting succulent forage chiefly for feeding livestock.

  5. Pleiotropy - Wikipedia

    en.wikipedia.org/wiki/Pleiotropy

    Photomicrograph of normal-shaped and sickle-shape red blood cells from a patient with sickle cell disease. Sickle cell anemia is a genetic disease that causes deformed red blood cells with a rigid, crescent shape instead of the normal flexible, round shape. [29] It is caused by a change in one nucleotide, a point mutation [30] in the HBB gene.

  6. Central Crisis Management Cell (Syria) - Wikipedia

    en.wikipedia.org/wiki/Central_Crisis_Management...

    The Central Crisis Management Cell (CCMC) (Arabic: خلية إدارة الأزمة السورية), also known as the Syrian Crisis Cell, was a secret security committee established by the Syrian government in March 2011 to coordinate the response to civilian protest and internal dissent.

  7. U.S. approves two sickle cell gene therapies, which doctors ...

    www.aol.com/news/u-approves-two-sickle-cell...

    Sickle cell disease is a rare, debilitating and life-threatening blood disorder with significant unmet need,” the FDA’s Dr. Nicole Verdun […] The post U.S. approves two sickle cell gene ...

  8. Parvovirus B19 - Wikipedia

    en.wikipedia.org/wiki/Parvovirus_B19

    Although most patients have a decrease of erythropoiesis (production of red blood cells) during parvovirus infection, it is most dangerous in patients with pre-existing bone marrow stress, for example sickle cell anemia or hereditary spherocytosis, [43] [44] and are therefore heavily dependent on erythropoiesis due to the reduced lifespan of ...

  9. Hemoglobin A - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_A

    However, HbAS does not cause vaso-occlusive crisis, which is known to be associated with sickle cell disease. [ 17 ] Patients that are homozygous for HbS have multi-stranded fibers that induce a change in shape of red blood cells from biconcave disks to elongated crescents.

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