Search results
Results From The WOW.Com Content Network
She travelled to the United States to study counselling for sickle-cell and thalassemia centres as courses were not then available in the UK. In 1979 she worked with Dr Milica Brozovic to create the first UK sickle-cell and thalassemia counselling centre in London Borough of Brent. This was the first of over 30 centres in the UK using the Brent ...
Harvey Akio Itano (Japanese: ハーベイ・アキオ・イタノ [1], November 3, 1920 – May 8, 2010) was an American biochemist best known for his work on the molecular basis of sickle cell anemia and other diseases.
Acquired asplenia occurs for several reasons: . Following splenectomy due to splenic rupture from trauma or because of tumor; After splenectomy with the goal of interfering with splenic function, as a treatment for diseases (e.g. idiopathic thrombocytopenic purpura, thalassemia, spherocytosis), in which the spleen's usual activity exacerbates the disease
Hemoglobin. The mean corpuscular hemoglobin concentration (MCHC) is a measure of the concentration of hemoglobin in a given volume of packed red blood cell.. It is calculated by dividing the hemoglobin by the hematocrit.
Photomicrograph of normal-shaped and sickle-shape red blood cells from a patient with sickle cell disease. Sickle cell anemia is a genetic disease that causes deformed red blood cells with a rigid, crescent shape instead of the normal flexible, round shape. [29] It is caused by a change in one nucleotide, a point mutation [30] in the HBB gene.
The ESR is decreased in polycythemia, hyperviscosity, sickle cell anemia, leukemia, chronic fatigue syndrome, [4] low plasma protein (due to liver or kidney disease) and congestive heart failure. Although increases in immunoglobulins usually increase the ESR, very high levels can reduce it again due to hyperviscosity of the plasma. [5]
These diseases are typically diseases in which chronic blood loss requires frequent blood transfusions, such as sickle cell anemia and thalassemia, though beta thalassemia minor has been associated with hemosiderin deposits in the liver in those with non-alcoholic fatty liver disease independent of any transfusions.
The direct and indirect Coombs tests, also known as antiglobulin test (AGT), are blood tests used in immunohematology.The direct Coombs test detects antibodies that are stuck to the surface of the red blood cells. [1]