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  2. Sickle cell disease - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_disease

    The most common type is known as sickle cell anemia. [2] ... The life expectancy in much of the developing world is unknown. [126] In 1975, about 7.3% of people with ...

  3. Woman with sickle cell disease celebrates 80th birthday ... - AOL

    www.aol.com/news/woman-sickle-cell-disease...

    McGill is one of the nation’s oldest people with sickle cell disease, living decades past age 52, the life expectancy of someone with the disease, which has a disproportionate effect on Black ...

  4. Sickle cell trait - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_trait

    Hematology. Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display the severe symptoms of sickle cell disease that occur in a person who has two copies of that allele (is homozygous). Those who are heterozygous for the sickle cell allele produce both ...

  5. Sideroblastic anemia - Wikipedia

    en.wikipedia.org/wiki/Sideroblastic_anemia

    Sideroblastic anemia, or sideroachrestic anemia, is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes). [1] In sideroblastic anemia, the body has iron available but cannot incorporate it into hemoglobin , which red blood cells need in order to transport oxygen efficiently.

  6. For people with sickle cell disease, ERs can mean life ... - AOL

    www.aol.com/news/people-sickle-cell-disease-ers...

    A sickle cell health crisis can escalate into life-threatening complications, but patients still struggle to get seen quickly in emergency rooms and also to get pain medicine.

  7. Balancing selection - Wikipedia

    en.wikipedia.org/wiki/Balancing_selection

    Sickle cell anemia is caused by the inheritance of an allele (HgbS) of the hemoglobin gene from both parents. In such individuals, the hemoglobin in red blood cells is extremely sensitive to oxygen deprivation, which results in shorter life expectancy.

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