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  2. Ehlers–Danlos syndrome - Wikipedia

    en.wikipedia.org/wiki/Ehlers–Danlos_syndrome

    But long-term use of NSAIDs is often a risk factor for gastrointestinal, renal, and blood-related side effects. It can worsen symptoms of mast cell activation syndrome, a disease that may be associated with EDS. Acetaminophen can be used to avoid the bleeding-related side effects of NSAIDs. [104]