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  2. Sickle cell retinopathy - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_retinopathy

    Proliferative sickle retinopathy is the most severe ocular complication of sickle cell disease. Even though PSCR begins in the first decade of life, the condition remains asymptomatic and unnoticed until visual symptoms occur due to vitreous hemorrhage or retinal detachment.

  3. Hemoglobin C - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_C

    It is possible for a person to have both the gene for hemoglobin S (the form associated with sickle cell anemia) and the gene for hemoglobin C; this state is called hemoglobin SC disease, and is generally more severe than hemoglobin C disease, but milder than sickle cell anemia. [2]

  4. Aplastic anemia - Wikipedia

    en.wikipedia.org/wiki/Aplastic_anemia

    However, in people with conditions where the cells die early (such as sickle cell disease), parvovirus infection can lead to severe anemia. [15] [16] More frequently, parvovirus B19 is associated with aplastic crisis, which involves only red blood cells (despite the name). Aplastic anemia involves all cell lines.

  5. Hereditary elliptocytosis - Wikipedia

    en.wikipedia.org/wiki/Hereditary_elliptocytosis

    Hereditary elliptocytosis, also known as ovalocytosis, is an inherited blood disorder in which an abnormally large number of the person's red blood cells are elliptical rather than the typical biconcave disc shape.

  6. Sickle cell nephropathy - Wikipedia

    en.wikipedia.org/wiki/Sickle_cell_nephropathy

    Sickle cell nephropathy is a type of kidney disease associated with sickle cell disease which causes kidney complications as a result of sickling of red blood cells in the small blood vessels. The hypertonic and relatively hypoxic environment of the renal medulla , coupled with the slow blood flow in the vasa recta , favors sickling of red ...

  7. Hemoglobin D-Punjab - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_D-Punjab

    People with hemoglobin D trait do not have Hemoglobin D disease or sickle cell disease. They cannot develop these diseases later in life. They cannot develop these diseases later in life. While Hemoglobin D can be detected without a DNA test, one is needed to ascertain that a person who carries Hemoglobin D carries hemoglobin D-Punjab.

  8. Hemoglobin A - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_A

    Some symptoms of sickle cell anemia include fever, fatigue from anemia, swelling of the hands and feet, stroke, and organ failure. [20] Current treatments include blood transfusions which aid with increasing the number of normal red blood cells, bone marrow transplants to help the patients body produce healthy red blood cells, and medications ...

  9. Heterozygote advantage - Wikipedia

    en.wikipedia.org/wiki/Heterozygote_advantage

    Sickle-cell anemia (SCA) is a genetic disorder caused by the presence of two incompletely recessive alleles. When a sufferer's red blood cells are exposed to low-oxygen conditions, the cells lose their healthy round shape and become sickle-shaped. This deformation of the cells can cause them to become lodged in capillaries, depriving other ...

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