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The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 96 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 97 ]
Los Angeles, [a] often referred to by its initials L.A., is the most populous city in the U.S. state of California.With an estimated 3,820,914 residents within the city limits as of 2023, [8] It is the second-most populous city in the United States, behind only New York City; it is also the commercial, financial and cultural center of Southern California.
This is an accepted version of this page This is the latest accepted revision, reviewed on 17 September 2024. Socioeconomic and political crisis in Venezuela in the 21st century This article is about the socioeconomic and political crisis in Venezuela. For other uses, see Venezuelan crisis (disambiguation). This article has multiple issues. Please help improve it or discuss these issues on the ...
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