McDonald joined the cast of MADtv in 1998, along with Andrew Bowen and Mo Collins, as a featured member, and has since become the member with the longest tenure in the history of the show. In due time, he would wind up leaving a big mark on MADtv with his memorable characters and outrageous humor. One of these characters was Stuart Larkin, a tyke who's rather tall for his age, and is emotionally distraught after the divorce between his mother (played by Collins) and his father, who left on Tuesday. Along with The Vancome Lady (Nicole Sullivan), Lorraine (Mo Collins), Ms. Swan (Alex Borstein), Bunifa Latifa Halifa Sharifa Jackson (Debra Wilson), etc., Stuart became one of the most famous characters on the sketch variety show.
Aside from Stuart, McDonald impressed with other characters, such as randy film producer Marvin Tikvah, Cal State Fullerton student Rusty Miller, nasty-mouthed Clyde, Abercrombie & Fitch model Cougar, depressed tow truck Persian Mofaz, and Fightin' Ron Fraser.
McDonald impressed with a variety of impressions, including favorite Bill O'Reilly, Bob Barker, Dr. Phil McGraw, John Kerry, John Ramsey, and Maury Povich.
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